This page is the HORIZON reference for all confirmed hantavirus activity in 2026.
Updated in real time from WHO Disease Outbreak News, CDC HAN, ECDC CDTR, PAHO, and
national health authority bulletins. Authoritative confirmed-case counts only.
2026 at a glance
Dominant event
MV Hondius Andes virus cluster (WHO DON 600)
Confirmed cases (MV Hondius cluster)
28 (as of latest WHO/ECDC bulletin)
Countries affected (cluster)
11 nationalities among confirmed cases
Causative serotype
Andes virus (ANDV), Hantavirus Pulmonary Syndrome
Suspected exposure site
Wildlife excursion near Ushuaia, Tierra del Fuego, Argentina
Vessel
MV Hondius (IMO 9818709), Oceanwide Expeditions, Netherlands flag
WHO notification
Disease Outbreak News DON 600, 25 March 2026
PAHO alert
Epidemiological Alert, 25 March 2026
Case-fatality (ANDV, historical)
30–50%
The MV Hondius cluster
The MV Hondius is a polar expedition vessel operated by
Oceanwide Expeditions
(Netherlands). In late February and early March 2026, the vessel completed two Antarctic
expedition voyages departing from Ushuaia, Argentina. Passengers participated in wildlife
excursions in the Tierra del Fuego region. The long-tailed pygmy rice rat
(Oligoryzomys longicaudatus) is the primary ANDV reservoir in the area;
aerosolisation of infected excreta during excursions is the suspected transmission mechanism.
Following the voyages, passengers from 11 countries reported Hantavirus Pulmonary Syndrome
(HPS). Argentine health authorities, WHO, ECDC, CDC, and PAHO co-ordinated responses.
Argentine Ministerio de Salud issued the first domestic alert. WHO published Disease Outbreak
News DON 600 on 25 March 2026.
Person-to-person transmission on the vessel has not been established. Andes virus is the
only orthohantavirus with documented person-to-person spread, but such transmission
requires prolonged, very close contact with symptomatic individuals.
Individual-level data: Oxford Kraemer Lab line list
A living CC0 individual-level dataset for the MV Hondius cluster is maintained by
Dr Moritz Kraemer
(University of Oxford), Sam Scarpino, and
Andrew Rambaut
(University of Edinburgh / Nextstrain).
The 28-column per-person dataset includes symptom onset date, clinical outcome, nationality,
treatment received, hospitalisation status, and Pathoplexus/GenBank genomic accession IDs.
Hosted at
github.com/kraemer-lab/Hondius_hantavirus_h2026.
HORIZON is the only public surveillance platform ingesting this dataset in real time.
Other hantavirus activity in 2026
Beyond the MV Hondius cluster, routine seasonal surveillance continues:
Puumala virus (PUUV) — northern Europe:
Finland, Germany, Sweden, Russia, Belgium, and other EU/EEA countries report ongoing HFRS
cases consistent with the 2025–26 bank vole (Myodes glareolus) population cycle.
Finland and Germany typically record the highest European PUUV burden during high-vole years.
Seoul virus (SEOV) — global:
SEOV in domestic and laboratory rats is reported globally at endemic background levels.
No unusual cluster activity in 2026 as of this update.
Hantaan virus (HTNV) — east Asia:
Seasonal HFRS continues in China (Shaanxi, Shandong), South Korea, and Russian Far East.
Endemic background levels consistent with prior years.
Americas — endemic activity:
Argentina, Chile, Brazil, and the United States report sporadic HPS cases in
rural areas with rodent contact, consistent with long-run endemic rates.
HORIZON's HantaNet integration links MV Hondius case records to the
NCBI RefSeq ANDV reference genome
(NC_003467 / NC_003468 / NC_003466 for S/M/L segments, Chile strain 9717869). The
Oxford Kraemer Lab line list records include Pathoplexus accession identifiers for cases with
genomic data, enabling direct linkage from epidemiological record to genomic reference.
HORIZON is the only public hantavirus surveillance platform aggregating 65+ sources with
NATO Admiralty source qualification, individual-level Oxford Kraemer Lab line list integration,
HantaNet genomic reference layer, and a free open-data API (CC BY 4.0). It is the most
comprehensive live hantavirus tracker available for 2026.
Hantavirus Pulmonary Syndrome (HPS) · CFR approximately 38 percent
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Nephropathia Epidemica (mild HFRS) · CFR less than 1 percent
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Hantavirus Pulmonary Syndrome (HPS) · CFR approximately 33 percent
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