Andes virus is the most lethal hantavirus serotype recognised in the Americas. It is endemic to the southern cone of South America and is the primary serotype implicated in the 2026 MV Hondius cluster. Symptoms appear 1 to 8 weeks after exposure and progress rapidly to cardiopulmonary collapse without intensive supportive care.
| Virus code | ANDV |
|---|---|
| Full name | Andes virus (ANDV) |
| Clinical syndrome | Hantavirus Pulmonary Syndrome (HPS) |
| ICD-10 code | A98.5 |
| Reservoir species | Oligoryzomys longicaudatus (long-tailed pygmy rice rat) |
| Endemic regions | Argentina, Chile, southern Patagonia, Tierra del Fuego |
| Case-fatality rate | 30 to 50 percent |
| Person-to-person | Andes virus is the only orthohantavirus with documented person-to-person transmission, predominantly between close household contacts. P2P has been linked to clusters in El Bolsón, Río Negro Province, Argentina (1996) and in Chile. |
Andes virus is the most lethal hantavirus serotype recognised in the Americas. It is endemic to the southern cone of South America and is the primary serotype implicated in the 2026 MV Hondius cluster. Symptoms appear 1 to 8 weeks after exposure and progress rapidly to cardiopulmonary collapse without intensive supportive care.
HORIZON ingests every WHO Disease Outbreak News bulletin, ECDC weekly Communicable Disease Threats Report, CDC HAN advisory, PAHO update, and peer-reviewed publication that mentions ANDV. Browse the live article feed or hit the JSON API for the raw data. Active incidents involving this serotype appear on the live outbreak map.
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